Protagonist Therapeutics (PTGX) Market Cap 2016–2026
As of January 27, 2026, Protagonist Therapeutics had a market cap of $5.194 billion, which increased by 0.95% compared to the previous trading day. Market capitalization, often referred to as market cap, represents the total value of a company's outstanding shares on the stock market and is a common measure of its overall size and valuation.
Data updated: Jan 27, 2026, 4:00 PM ET
Protagonist Therapeutics, Inc. (PTGX)
🌍 United States📈 NASDAQ🏭 Health Care🏢 Biotechnology
Note: Each point on the chart represents the market capitalization at the end of the trading day. Source: Data compiled from EDGAR filings, Bloomberg and Yahoo Finance.
📈 Protagonist Therapeutics Market Cap History by Year and Month
Protagonist Therapeutics Market Cap History by Year and Month
Year / Month
Market Cap
% Change
2026
$5.194B
▼ 4.87%
$5.194B
▼ 4.87%
2025
$5.46B
▲ 131.75%
$5.46B
▼ 2.97%
$5.627B
▲ 14.49%
$4.915B
▲ 18.46%
$4.149B
▲ 12.93%
$3.674B
▲ 9.64%
$3.351B
▼ 2.39%
$3.433B
▲ 16.69%
$2.942B
▲ 3.59%
$2.84B
▼ 5.18%
$2.995B
▲ 29.82%
$2.307B
— 0.00%
$2.307B
▼ 2.08%
2024
$2.356B
▲ 78.08%
$2.356B
▼ 9.73%
$2.61B
▼ 4.47%
$2.732B
▲ 2.02%
$2.678B
▲ 6.02%
$2.526B
▲ 14.56%
$2.205B
▲ 8.51%
$2.032B
▲ 23.08%
$1.651B
▲ 12.08%
$1.473B
▼ 13.05%
$1.694B
▼ 4.35%
$1.771B
▲ 22.73%
$1.443B
▲ 9.07%
2023
$1.323B
▲ 146.37%
$1.323B
▲ 26.00%
$1.05B
▲ 25.15%
$0.839B
▼ 12.60%
$0.96B
▼ 15.79%
$1.14B
▲ 2.15%
$1.116B
▼ 29.72%
$1.588B
▲ 6.36%
$1.493B
▲ 15.38%
$1.294B
▲ 9.38%
$1.183B
▲ 47.88%
$0.8B
▲ 21.95%
$0.656B
▲ 22.16%
2022
$0.537B
▼ 67.18%
$0.537B
▲ 38.05%
$0.389B
▼ 2.51%
$0.399B
▼ 3.86%
$0.415B
▼ 3.04%
$0.428B
▼ 12.30%
$0.488B
▲ 26.75%
$0.385B
▼ 9.62%
$0.426B
▼ 3.62%
$0.442B
▼ 61.57%
$1.15B
▼ 2.13%
$1.175B
▼ 16.13%
$1.401B
▼ 14.36%
2021
$1.636B
▲ 85.49%
$1.636B
▲ 1.93%
$1.605B
▲ 7.94%
$1.487B
▲ 75.98%
$0.845B
▼ 63.36%
$2.306B
▼ 1.87%
$2.35B
▲ 10.17%
$2.133B
▲ 38.24%
$1.543B
▲ 21.31%
$1.272B
▲ 11.78%
$1.138B
▲ 10.16%
$1.033B
▲ 14.02%
$0.906B
▲ 2.72%
2020
$0.882B
▲ 359.38%
$0.882B
▼ 4.55%
$0.924B
▲ 27.45%
$0.725B
▼ 0.55%
$0.729B
▼ 11.64%
$0.825B
▲ 42.49%
$0.579B
▼ 10.92%
$0.65B
▲ 7.08%
$0.607B
▲ 228.11%
$0.185B
▼ 4.64%
$0.194B
▼ 8.92%
$0.213B
▲ 3.40%
$0.206B
▲ 7.29%
2019
$0.192B
▲ 23.08%
$0.192B
▼ 18.99%
$0.237B
▼ 35.25%
$0.366B
▲ 11.93%
$0.327B
▼ 4.39%
$0.342B
▲ 17.93%
$0.29B
▲ 2.47%
$0.283B
▲ 20.43%
$0.235B
▼ 2.89%
$0.242B
▼ 17.69%
$0.294B
▲ 57.22%
$0.187B
▼ 1.06%
$0.189B
▲ 21.15%
2018
$0.156B
▼ 64.30%
$0.156B
▼ 0.64%
$0.157B
▼ 18.65%
$0.193B
▼ 22.18%
$0.248B
▲ 6.90%
$0.232B
▲ 57.82%
$0.147B
▲ 3.52%
$0.142B
▼ 7.79%
$0.154B
▼ 15.85%
$0.183B
▲ 0.55%
$0.182B
▼ 49.16%
$0.358B
▼ 25.73%
$0.482B
▲ 10.30%
2017
$0.437B
▲ 19.07%
$0.437B
▲ 6.59%
$0.41B
▲ 33.55%
$0.307B
▲ 2.68%
$0.299B
▲ 8.33%
$0.276B
▲ 33.98%
$0.206B
▲ 7.85%
$0.191B
▲ 1.60%
$0.188B
▲ 9.94%
$0.171B
▼ 20.83%
$0.216B
▼ 7.30%
$0.233B
▼ 22.85%
$0.302B
▼ 17.71%
2016
$0.367B
▲ 92.15%
$0.367B
▼ 11.99%
$0.417B
▲ 32.80%
$0.314B
▼ 11.05%
$0.353B
▲ 78.28%
$0.198B
▲ 3.66%
All market cap values reflect closing prices for the period shown.
📊 Protagonist Therapeutics Market Cap and Other Industry Peers
Below are selected companies from the Biotechnology sector / subsector:
Data reflect the most recent market capitalization values available.
💡 What Is Market Capitalization and How Do We Calculate It?
For Protagonist Therapeutics, Inc. (PTGX), market capitalization represents the total market value of the company’s publicly traded shares. It helps investors understand Protagonist Therapeutics’s size within the health care sector and compare it with other companies in the same industry.
In most cases, market capitalization is calculated by multiplying the current share price by the number of basic shares outstanding. Basic shares represent the actual number of common shares that currently exist, without including potential future shares from employee stock options, RSUs, warrants, or convertible securities. For example, if Protagonist Therapeutics had one million basic shares and each traded at $50, its market capitalization would be $50 million.
Formula: Market Cap = Share Price × Shares Outstanding
The value of Protagonist Therapeutics’s market capitalization changes throughout the trading day because it mainly depends on the current share price. The number of shares outstanding typically remains stable unless the company issues new shares, buys back its own stock, or grants stock options to employees.
Based on the latest data, Protagonist Therapeutics had a market capitalization of $5.194 billion, placing it in the mid-cap category within the health care industry.
Disclaimer: Despite all efforts, there may still be minor inaccuracies present in the data.