As of November 13, 2026, Ionis Pharmaceuticals had a market cap of $4.836 billion, which increased by 6.40% compared to the previous trading day. Market capitalization, often referred to as market cap, represents the total value of a company's outstanding shares on the stock market and is a common measure of its overall size and valuation.
Data updated: Nov 13, 2026, 4:00 PM ET
Ionis Pharmaceuticals Inc. (IONS)
🌍 United States📈 NASDAQ🏭 Health Care🏢 Biotechnology
Note: Each point on the chart represents the market capitalization at the end of the trading day. Source: Data compiled from
EDGAR filings,
Bloomberg
and Yahoo Finance.
📈 Ionis Pharmaceuticals Market Cap History by Year and Month
Ionis Pharmaceuticals Market Cap History by Year and Month
Year / Month
Market Cap
% Change
2026
$4.836B
▼ 62.25%
$4.836B
▼ 32.92%
$7.209B
▼ 2.53%
$7.396B
▼ 26.03%
$9.998B
▲ 16.59%
$8.575B
▼ 34.79%
$13.15B
▲ 4.03%
$12.64B
▲ 2.27%
$12.36B
▼ 0.32%
$12.4B
▼ 5.63%
$13.14B
▼ 1.87%
$13.39B
▲ 4.53%
2025
$12.81B
▲ 132.04%
$12.81B
▼ 4.40%
$13.4B
▲ 11.39%
$12.03B
▲ 15.34%
$10.43B
▲ 53.47%
$6.796B
▼ 0.80%
$6.851B
▲ 8.95%
$6.288B
▲ 17.91%
$5.333B
▲ 9.10%
$4.888B
▲ 1.88%
$4.798B
▼ 9.06%
$5.276B
▲ 4.74%
$5.037B
▼ 8.76%
2024
$5.521B
▼ 23.94%
$5.521B
▼ 2.15%
$5.642B
▼ 6.93%
$6.062B
▼ 4.11%
$6.322B
▼ 9.32%
$6.971B
▼ 3.60%
$7.232B
▲ 3.95%
$6.957B
▲ 26.86%
$5.484B
▼ 8.87%
$6.018B
▼ 4.76%
$6.318B
▼ 4.11%
$6.589B
▼ 11.17%
$7.418B
▲ 2.20%
2023
$7.258B
▲ 35.28%
$7.258B
▲ 2.26%
$7.097B
▲ 11.75%
$6.351B
▼ 2.31%
$6.501B
▲ 12.64%
$5.772B
▼ 2.69%
$5.932B
▲ 0.97%
$5.874B
▲ 0.37%
$5.852B
▲ 15.63%
$5.061B
▼ 0.99%
$5.112B
▼ 0.40%
$5.132B
▼ 9.39%
$5.664B
▲ 5.57%
2022
$5.365B
▲ 24.86%
$5.365B
▼ 7.40%
$5.794B
▼ 7.70%
$6.277B
▼ 0.07%
$6.282B
▲ 4.08%
$6.035B
▲ 13.29%
$5.327B
▲ 1.46%
$5.251B
▲ 1.39%
$5.179B
▼ 0.65%
$5.213B
▼ 0.72%
$5.25B
▲ 11.01%
$4.73B
▲ 5.33%
$4.49B
▲ 4.50%
2021
$4.297B
▼ 45.86%
$4.297B
▲ 14.83%
$3.742B
▼ 16.85%
$4.5B
▼ 4.96%
$4.735B
▼ 15.63%
$5.612B
▲ 7.05%
$5.242B
▼ 6.81%
$5.625B
▲ 7.13%
$5.251B
▼ 13.01%
$6.036B
▼ 4.73%
$6.336B
▼ 14.16%
$7.381B
▼ 12.46%
$8.432B
▲ 6.24%
2020
$7.937B
▼ 6.39%
$7.937B
▲ 12.33%
$7.065B
▲ 7.63%
$6.565B
▼ 1.03%
$6.633B
▼ 12.88%
$7.614B
▼ 5.32%
$8.041B
▼ 2.23%
$8.224B
▲ 5.02%
$7.831B
▲ 1.22%
$7.736B
▲ 17.48%
$6.585B
▼ 6.85%
$7.07B
▼ 13.62%
$8.185B
▼ 3.46%
2019
$8.478B
▲ 13.70%
$8.478B
▼ 5.77%
$8.997B
▲ 14.79%
$7.838B
▼ 6.98%
$8.426B
▼ 5.13%
$8.881B
▼ 3.95%
$9.246B
▲ 2.53%
$9.018B
▼ 2.03%
$9.205B
▼ 11.39%
$10.388B
▼ 7.59%
$11.241B
▲ 14.41%
$9.825B
▲ 22.81%
$8B
▲ 7.29%
2018
$7.456B
▲ 18.78%
$7.456B
▼ 7.01%
$8.019B
▲ 17.64%
$6.817B
▼ 3.73%
$7.08B
▲ 12.89%
$6.272B
▲ 4.60%
$5.996B
▲ 14.64%
$5.23B
▼ 10.68%
$5.856B
▲ 8.41%
$5.401B
▼ 2.32%
$5.529B
▼ 16.52%
$6.624B
▲ 0.91%
$6.564B
▲ 4.56%
2017
$6.277B
▲ 8.29%
$6.277B
▼ 9.35%
$6.925B
▼ 2.70%
$7.117B
▲ 12.89%
$6.305B
▼ 5.45%
$6.668B
▲ 2.49%
$6.505B
▲ 3.01%
$6.316B
▲ 11.26%
$5.677B
▼ 4.91%
$5.97B
▲ 19.88%
$4.98B
▼ 19.14%
$6.159B
▲ 13.78%
$5.413B
▼ 6.62%
2016
$5.797B
▼ 22.22%
$5.797B
▲ 9.30%
$5.304B
▲ 68.51%
$3.147B
▼ 29.09%
$4.439B
▲ 23.81%
$3.585B
▲ 1.63%
$3.528B
▲ 25.33%
$2.815B
▲ 2.70%
$2.74B
▼ 44.62%
$4.948B
▲ 1.21%
$4.889B
▲ 17.25%
$4.17B
▼ 11.00%
$4.685B
▼ 37.14%
2015
$7.453B
▲ 1.93%
$7.453B
▲ 1.65%
$7.332B
▲ 26.87%
$5.779B
▲ 19.12%
$4.852B
▼ 19.40%
$6.02B
▼ 8.65%
$6.589B
▼ 4.49%
$6.899B
▼ 14.39%
$8.059B
▲ 18.69%
$6.79B
▼ 10.83%
$7.615B
▼ 6.68%
$8.16B
▲ 0.56%
$8.114B
▲ 10.97%
2014
$7.312B
▲ 57.59%
$7.312B
▲ 19.51%
$6.118B
▲ 12.58%
$5.435B
▲ 18.62%
$4.582B
▼ 4.53%
$4.799B
▲ 31.60%
$3.647B
▼ 10.04%
$4.054B
▲ 17.99%
$3.436B
▲ 9.83%
$3.128B
▼ 38.41%
$5.079B
▼ 15.08%
$5.981B
▲ 0.57%
$5.947B
▲ 28.16%
2013
$4.64B
▲ 337.98%
$4.64B
▲ 3.14%
$4.499B
▲ 16.57%
$3.859B
▼ 11.37%
$4.355B
▲ 46.20%
$2.978B
▼ 9.67%
$3.297B
▲ 18.24%
$2.789B
▲ 23.88%
$2.251B
▼ 2.75%
$2.315B
▲ 34.18%
$1.725B
▲ 15.24%
$1.497B
▲ 1.52%
$1.475B
▲ 39.18%
2012
$1.059B
▲ 47.34%
$1.059B
▲ 13.78%
$0.931B
▲ 6.50%
$0.874B
▼ 38.23%
$1.415B
▲ 3.38%
$1.369B
▲ 12.61%
$1.216B
▲ 1.14%
$1.202B
▲ 21.33%
$0.991B
▲ 23.63%
$0.801B
▼ 8.78%
$0.879B
▼ 3.71%
$0.912B
▲ 11.78%
$0.816B
▲ 13.53%
2011
$0.719B
▼ 28.51%
$0.719B
▼ 2.83%
$0.74B
▼ 10.49%
$0.827B
▲ 22.27%
$0.676B
▼ 9.42%
$0.746B
▼ 13.28%
$0.861B
▼ 5.68%
$0.913B
▼ 0.73%
$0.919B
▼ 1.60%
$0.934B
▲ 3.77%
$0.9B
▼ 0.88%
$0.908B
▲ 0.41%
$0.904B
▼ 10.08%
2010
$1.006B
▼ 8.41%
$1.006B
▲ 7.38%
$0.937B
▲ 3.28%
$0.907B
▲ 8.81%
$0.834B
▲ 7.61%
$0.775B
▼ 20.98%
$0.98B
▲ 3.34%
$0.948B
▲ 4.04%
$0.912B
▼ 14.49%
$1.066B
▼ 1.56%
$1.083B
▲ 23.67%
$0.876B
▼ 20.62%
$1.103B
▲ 0.45%
2009
$1.098B
▼ 20.16%
$1.098B
▲ 4.23%
$1.054B
▼ 15.47%
$1.246B
▼ 13.04%
$1.433B
▼ 9.68%
$1.587B
▼ 11.55%
$1.794B
▲ 10.79%
$1.62B
▲ 19.60%
$1.354B
▼ 11.51%
$1.53B
▲ 4.46%
$1.465B
▲ 16.72%
$1.255B
▼ 8.43%
$1.371B
▼ 0.35%
2008
$1.375B
▲ 0.10%
$1.375B
▲ 23.63%
$1.113B
▼ 17.70%
$1.352B
▼ 16.76%
$1.624B
▼ 3.96%
$1.691B
▲ 3.42%
$1.635B
▲ 25.68%
$1.301B
▼ 3.54%
$1.349B
▲ 23.12%
$1.095B
▼ 16.51%
$1.312B
▲ 4.44%
$1.256B
▼ 7.69%
$1.361B
▼ 0.95%
2007
$1.374B
▲ 62.78%
$1.374B
▼ 10.67%
$1.538B
▲ 0.40%
$1.532B
▲ 23.62%
$1.239B
▲ 21.31%
$1.022B
▲ 18.54%
$0.862B
▲ 7.88%
$0.799B
▼ 3.78%
$0.83B
▼ 1.66%
$0.844B
▲ 10.42%
$0.765B
▲ 1.89%
$0.75B
▼ 12.22%
$0.855B
▲ 1.28%
2006
$0.844B
▲ 123.12%
$0.844B
▲ 9.13%
$0.774B
▲ 21.99%
$0.634B
▲ 19.53%
$0.53B
▼ 6.02%
$0.564B
▲ 28.83%
$0.438B
▼ 0.66%
$0.441B
▼ 22.50%
$0.569B
▼ 8.74%
$0.624B
▼ 4.77%
$0.655B
▲ 12.81%
$0.58B
▲ 48.61%
$0.391B
▲ 3.24%
2005
$0.378B
▲ 11.62%
$0.378B
▲ 3.35%
$0.366B
▲ 16.82%
$0.313B
▼ 14.06%
$0.365B
▲ 24.19%
$0.294B
▲ 10.48%
$0.266B
▲ 18.16%
$0.225B
▲ 6.81%
$0.211B
▲ 26.23%
$0.167B
▼ 25.06%
$0.223B
▼ 4.56%
$0.233B
▼ 20.08%
$0.292B
▼ 13.90%
2004
$0.339B
▼ 6.14%
$0.339B
▲ 25.37%
$0.27B
▲ 1.29%
$0.267B
▼ 4.90%
$0.281B
▼ 18.32%
$0.344B
▲ 19.12%
$0.288B
▼ 12.02%
$0.328B
▼ 9.42%
$0.362B
▼ 11.09%
$0.407B
▼ 6.31%
$0.435B
▼ 1.62%
$0.442B
▼ 10.27%
$0.492B
▲ 36.31%
2003
$0.361B
▼ 0.76%
$0.361B
▲ 10.36%
$0.327B
▼ 11.41%
$0.369B
▲ 1.99%
$0.362B
▼ 1.34%
$0.367B
▲ 27.71%
$0.287B
▼ 2.81%
$0.296B
▼ 16.42%
$0.354B
▲ 15.55%
$0.306B
▲ 54.47%
$0.198B
▼ 20.09%
$0.248B
▼ 24.99%
$0.331B
▼ 9.10%
2002
$0.364B
▼ 69.49%
$0.364B
▼ 23.53%
$0.476B
▼ 11.58%
$0.538B
▼ 0.78%
$0.542B
▼ 1.30%
$0.55B
▲ 14.58%
$0.48B
▼ 6.91%
$0.515B
▲ 1.17%
$0.509B
▼ 25.48%
$0.683B
▼ 21.25%
$0.868B
▲ 9.61%
$0.792B
▼ 15.36%
$0.935B
▼ 21.59%
2001
$1.193B
▲ 187.76%
$1.193B
▲ 11.33%
$1.071B
▲ 9.59%
$0.978B
▲ 35.71%
$0.72B
▲ 4.60%
$0.689B
▲ 36.17%
$0.506B
▲ 1.61%
$0.498B
▲ 3.25%
$0.482B
▲ 9.09%
$0.442B
▲ 19.07%
$0.371B
▼ 14.94%
$0.436B
▼ 12.12%
$0.496B
▲ 19.78%
2000
$0.414B
▲ 109.80%
$0.414B
▲ 16.44%
$0.356B
▼ 10.27%
$0.397B
▼ 10.28%
$0.442B
▼ 11.96%
$0.502B
▲ 16.11%
$0.433B
▼ 22.27%
$0.557B
▲ 69.24%
$0.329B
▼ 16.85%
$0.395B
▼ 20.89%
$0.5B
▲ 11.97%
$0.446B
▲ 80.80%
$0.247B
▲ 25.00%
1999
$0.198B
▼ 43.55%
$0.198B
▼ 56.70%
$0.456B
▲ 35.14%
$0.338B
▲ 3.35%
$0.327B
▲ 14.05%
$0.286B
▼ 2.41%
$0.294B
▲ 1.84%
$0.288B
▲ 4.15%
$0.277B
▼ 2.99%
$0.285B
▲ 15.97%
$0.246B
▼ 24.95%
$0.328B
▼ 12.68%
$0.375B
▲ 7.25%
1998
$0.35B
▲ 6.61%
$0.35B
▲ 14.46%
$0.306B
▲ 18.18%
$0.259B
▼ 15.38%
$0.306B
▲ 57.01%
$0.195B
▼ 39.58%
$0.322B
▼ 12.33%
$0.368B
▼ 1.13%
$0.372B
▼ 2.63%
$0.382B
▼ 6.56%
$0.409B
▲ 13.66%
$0.36B
▼ 1.91%
$0.367B
▲ 11.68%
1997
$0.328B
▼ 30.40%
$0.328B
▼ 16.72%
$0.394B
▼ 9.89%
$0.437B
▼ 7.72%
$0.474B
▲ 18.97%
$0.398B
▲ 13.68%
$0.35B
▼ 9.01%
$0.385B
▼ 7.15%
$0.415B
▲ 6.78%
$0.389B
▼ 1.67%
$0.395B
▼ 22.29%
$0.508B
▲ 20.16%
$0.423B
▼ 10.28%
1996
$0.472B
▲ 60.84%
$0.472B
▲ 12.11%
$0.421B
▲ 0.77%
$0.417B
▲ 0.78%
$0.414B
▲ 23.19%
$0.336B
▼ 9.48%
$0.371B
▼ 21.84%
$0.475B
▲ 3.45%
$0.459B
▲ 42.16%
$0.323B
▲ 10.11%
$0.294B
▼ 7.00%
$0.316B
▼ 13.04%
$0.363B
▲ 23.79%
1995
$0.293B
▲ 271.91%
$0.293B
▲ 15.38%
$0.254B
▲ 12.35%
$0.226B
▼ 3.05%
$0.233B
▼ 4.12%
$0.243B
▼ 6.73%
$0.261B
▲ 2.97%
$0.253B
▲ 11.28%
$0.228B
▲ 64.29%
$0.139B
▲ 5.66%
$0.131B
▲ 18.26%
$0.111B
▼ 4.26%
$0.116B
▲ 46.95%
1994
$78.84M
▼ 37.77%
$78.84M
▼ 20.00%
$98.55M
▲ 29.03%
$76.376M
▼ 22.50%
$98.55M
▲ 5.48%
$93.433M
▼ 9.52%
$0.103B
▼ 22.22%
$0.133B
▼ 3.52%
$0.138B
▼ 9.68%
$0.152B
▲ 8.77%
$0.14B
▼ 2.13%
$0.143B
▼ 3.17%
$0.148B
▲ 16.67%
1993
$0.127B
▼ 0.27%
$0.127B
▲ 22.67%
$0.103B
▼ 17.19%
$0.125B
▲ 28.00%
$97.438M
▲ 0.19%
$97.25M
▲ 6.38%
$91.415M
▼ 7.84%
$99.195M
▼ 5.56%
$0.105B
▲ 14.89%
$91.415M
▼ 4.08%
$95.305M
▲ 21.90%
$78.18M
▼ 15.79%
$92.839M
▼ 26.92%
1992
$0.127B
▼ 28.04%
$0.127B
▼ 14.30%
$0.148B
▲ 91.67%
$77.34M
— 0.00%
$77.34M
▼ 17.18%
$93.38M
▼ 6.45%
$99.82M
▼ 6.06%
$0.106B
▼ 15.25%
$0.125B
▲ 5.41%
$0.119B
▼ 15.91%
$0.141B
▼ 18.39%
$0.173B
▼ 16.92%
$0.209B
▲ 18.18%
1991
$0.177B
N/A
$0.177B
▲ 23.96%
$0.142B
▼ 32.50%
$0.211B
▲ 19.40%
$0.177B
▼ 7.96%
$0.192B
▲ 28.07%
$0.15B
▲ 78.90%
$83.794M
▲ 7.89%
$77.663M
N/A
All market cap values reflect closing prices for the period shown.
📊 Ionis Pharmaceuticals Market Cap and Other Industry Peers
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